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Diabetes
8 trials
DCCT
The Diabetes Control and Complications Trial randomized 1,441 type 1 diabetes patients to intensive versus conventional insulin th...
UKPDS
The UK Prospective Diabetes Study followed over 5,000 newly diagnosed type 2 diabetes patients for a median of 10 years. Intensive...
Diabetes Prevention Program
The DPP randomized 3,234 people with impaired glucose tolerance to metformin, intensive lifestyle modification, or placebo. Lifest...
LOOK AHEAD
LOOK AHEAD randomized over 5,100 overweight or obese adults with type 2 diabetes to intensive lifestyle intervention targeting 7 p...
ACCORD
The Action to Control Cardiovascular Risk in Diabetes trial tested intensive glucose control targeting HbA1c under 6.0 percent in ...
ADVANCE
ADVANCE randomized 11,140 type 2 diabetes patients to intensive gliclazide based glucose control or standard therapy. Intensive co...
EMPA-REG OUTCOME
EMPA-REG OUTCOME randomized 7,020 type 2 diabetes patients with cardiovascular disease to the SGLT2 inhibitor empagliflozin or pla...
LEADER
The Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results trial randomized 9,340 type 2 diabetes...