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MTA Study
About the Trial
The Multimodal Treatment Study of Children with ADHD, sponsored by the US National Institute of Mental Health, randomized 579 children aged 7 to 9 to 14 months of carefully titrated medication management, intensive behavioral treatment, the combination, or referral to community care. Medication management and combined treatment improved core ADHD symptoms more than behavioral treatment or routine community care, while the combination offered modest additional benefits on some functional outcomes and allowed lower doses. Long term follow up showed that differences between groups faded within a few years, fueling continuing debate about the durability of stimulant benefits and the role of behavioral approaches.
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