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Neurology

6 trials

NINDS rt-PA Stroke Trial

TreatmentNeurology1995

The NINDS trial randomized 624 acute ischemic stroke patients to intravenous tPA or placebo within 3 hours of onset. At 3 months, ...

MR CLEAN

TreatmentNeurology2014

The Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands randomized 500 pa...

NASCET

PreventionNeurology1991

The North American Symptomatic Carotid Endarterectomy Trial randomized 2,885 patients with recent TIA or minor stroke and carotid ...

CLARITY-AD

TreatmentNeurology2022

The Clarity AD trial randomized 1,795 early Alzheimer patients to the anti amyloid antibody lecanemab or placebo for 18 months. Le...

ECASS III

TreatmentNeurology2008

The third European Cooperative Acute Stroke Study randomized 821 patients with acute ischemic stroke to intravenous alteplase or p...

DAWN

TreatmentNeurology2018

DAWN randomized 206 patients with large vessel occlusion strokes, last seen well 6 to 24 hours earlier, whose clinical deficit was...