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Critical Care

8 trials

ARDS Network ARMA

TreatmentCritical Care2000

The ARDS Network trial randomized 861 patients with acute respiratory distress syndrome to traditional 12 mL per kg tidal volumes ...

NICE-SUGAR

TreatmentCritical Care2009

The Normoglycemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation trial randomized 6,104 ICU patients...

SAFE

TreatmentCritical Care2004

The Saline versus Albumin Fluid Evaluation trial randomized 6,997 ICU patients to 4 percent albumin or normal saline for fluid res...

TRICC

TreatmentCritical Care1999

The Transfusion Requirements in Critical Care trial randomized 838 euvolemic ICU patients to restrictive transfusion at hemoglobin...

CRASH-2

TreatmentCritical Care2010

The Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage trial randomized 20,211 trauma patients with signific...

EOLIA

TreatmentCritical Care2018

The ECMO to Rescue Lung Injury in Severe ARDS trial randomized 249 patients with very severe ARDS to early VV ECMO or conventional...

Early Goal-Directed Therapy Trial

TreatmentCritical Care2001

Emanuel Rivers and colleagues at Henry Ford Hospital randomized 263 patients with severe sepsis or septic shock in the emergency d...

PROWESS

TreatmentCritical Care2001

PROWESS randomized 1,690 patients with severe sepsis to drotrecogin alfa activated, a recombinant form of activated protein C, or ...